KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
24.24
Human Site:
Y286
Identified Species:
48.48
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
Y286
R
L
R
Q
K
S
T
Y
T
S
Y
P
K
A
E
Chimpanzee
Pan troglodytes
XP_511742
777
85768
Y286
L
V
S
Q
K
S
T
Y
T
S
Y
P
K
A
E
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
Y286
R
L
R
Q
K
S
T
Y
T
S
Y
P
K
A
E
Dog
Lupus familis
XP_540486
782
86005
T290
K
S
A
Y
A
A
A
T
A
T
Y
P
K
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
Y286
R
M
R
Q
K
T
T
Y
T
A
H
P
K
A
E
Rat
Rattus norvegicus
Q9JJ50
776
86228
Y286
R
M
R
Q
K
S
T
Y
T
A
H
P
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
Y286
R
M
R
Q
K
T
T
Y
S
M
Y
P
K
A
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
P284
S
E
A
E
Q
Q
K
P
K
L
Q
S
L
P
P
Honey Bee
Apis mellifera
XP_393989
830
92147
R285
K
E
K
K
R
G
N
R
A
A
K
I
N
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
P283
I
V
S
S
A
P
A
P
E
P
E
L
D
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
R188
K
K
F
S
L
L
N
R
K
H
H
C
R
S
C
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
L283
K
R
A
L
A
M
S
L
E
E
V
K
S
Y
S
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
80
100
33.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
86.6
100
53.3
N.A.
100
100
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
13.3
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
25
9
17
0
17
25
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% D
% Glu:
0
17
0
9
0
0
0
0
17
9
9
0
0
0
59
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
25
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
34
9
9
9
50
0
9
0
17
0
9
9
59
0
0
% K
% Leu:
9
17
0
9
9
9
0
9
0
9
0
9
9
0
0
% L
% Met:
0
25
0
0
0
9
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
17
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
9
0
17
0
9
0
59
0
25
17
% P
% Gln:
0
0
0
50
9
9
0
0
0
0
9
0
0
0
0
% Q
% Arg:
42
9
42
0
9
0
0
17
0
0
0
0
9
0
0
% R
% Ser:
9
9
17
17
0
34
9
0
9
25
0
9
9
17
9
% S
% Thr:
0
0
0
0
0
17
50
9
42
9
0
0
0
0
0
% T
% Val:
0
17
0
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
50
0
0
42
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _